N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-leucine
Fmoc-N-methyl-D-leucine
CAS: 103478-63-3
Molecular Formula: C22H25NO4
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-leucine - Names and Identifiers
| Name | Fmoc-N-methyl-D-leucine |
| Synonyms | FMOC-D-MELEU-OH Fmoc-D-N-Me-Leu-OH FMOC-N-ME-D-LEU-OH FMOC-N-METHYL-D-LEUCINE Fmoc-N-methyl-D-leucine FMOC-N-ALPHA-METHYL-D-LEUCINE N-ALPHA-FMOC-N-ALPHA-METHYL-D-LEUCINE N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-leucine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-D-LEUCINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-D-LEUCINE |
| CAS | 103478-63-3 |
| InChI | InChI=1/C22H25NO4/c1-14(2)12-20(21(24)25)23(3)22(26)27-13-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,14,19-20H,12-13H2,1-3H3,(H,24,25)/t20-/m1/s1 |
| InChIKey | BUJQSIPFDWLNDC-HXUWFJFHSA-N |
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-leucine - Physico-chemical Properties
| Molecular Formula | C22H25NO4 |
| Molar Mass | 367.44 |
| Density | 1.194±0.06 g/cm3(Predicted) |
| Melting Point | 108-116 °C |
| Boling Point | 537.3±29.0 °C(Predicted) |
| Flash Point | 278.7°C |
| Solubility | Soluble in clear solution (0.3 gram in 2 ml DMF). |
| Vapor Presure | 2.25E-12mmHg at 25°C |
| Appearance | Powder |
| Color | Off-white |
| BRN | 7350417 |
| pKa | 3.93±0.21(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.581 |
| MDL | MFCD00235877 |
| Physical and Chemical Properties | Storage Conditions: 2-8 ℃ WGK Germany:3 |
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-leucine - Risk and Safety
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-leucine - Introduction
Fmoc-N-Methyl-D-Leucine is a chemical with a variety of properties and uses. Here is the relevant information:
Properties: Fmoc-N-methyl-D-leucine is a white or off-white solid, usually with high solubility. It is an amino acid derivative with a specific structure in which the N-methyl-D-leucine unit is linked to other chemical groups through an Fmoc (9H-fluoroformamido) protecting group.
Purpose: Fmoc-N-methyl-D-leucine has a wide range of applications in chemical synthesis and biological research. It is often used as a raw material for the synthesis of polypeptides and proteins, especially in solid phase synthesis, and can be used as an additive for the synthesis of custom compounds. In addition, Fmoc-N-methyl-D-leucine can also be used to synthesize biologically active products and has potential in the fields of drug development and bioengineering.
Preparation Method: The preparation of Fmoc-N-methyl-D-leucine is usually carried out by a chemical synthesis method. A common method is to use leucine as the starting material, through a series of reaction steps, including the introduction of protecting groups and conversion, and finally obtain the product Fmoc-N-methyl-D-leucine.
Safety information: When using Fmoc-N-methyl-D-leucine, you need to pay attention to safety measures. The substance may cause irritation to the eyes, skin and respiratory tract, so personal protective equipment should be worn to avoid direct contact. During the operation, the laboratory safety procedures should be followed and good ventilation should be ensured. If there is an accident, should immediately take appropriate first aid measures, and medical treatment.
Properties: Fmoc-N-methyl-D-leucine is a white or off-white solid, usually with high solubility. It is an amino acid derivative with a specific structure in which the N-methyl-D-leucine unit is linked to other chemical groups through an Fmoc (9H-fluoroformamido) protecting group.
Purpose: Fmoc-N-methyl-D-leucine has a wide range of applications in chemical synthesis and biological research. It is often used as a raw material for the synthesis of polypeptides and proteins, especially in solid phase synthesis, and can be used as an additive for the synthesis of custom compounds. In addition, Fmoc-N-methyl-D-leucine can also be used to synthesize biologically active products and has potential in the fields of drug development and bioengineering.
Preparation Method: The preparation of Fmoc-N-methyl-D-leucine is usually carried out by a chemical synthesis method. A common method is to use leucine as the starting material, through a series of reaction steps, including the introduction of protecting groups and conversion, and finally obtain the product Fmoc-N-methyl-D-leucine.
Safety information: When using Fmoc-N-methyl-D-leucine, you need to pay attention to safety measures. The substance may cause irritation to the eyes, skin and respiratory tract, so personal protective equipment should be worn to avoid direct contact. During the operation, the laboratory safety procedures should be followed and good ventilation should be ensured. If there is an accident, should immediately take appropriate first aid measures, and medical treatment.
Last Update：2024-04-09 20:49:11
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Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
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